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errrrrrrrm aspirin has no thrombolytic effect, it acts only to prevent the clot from getting any larger or new clots from forming....
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Thats not true. The thinning of the blood is caused by action on the platlets (that give blood its thickness) - when the asprin thins the blood, it also attacks the platlets of the clot. (not as good as a good thrombolytic drug but it is still partially effective) - and can be administered withough a degree in medicine! Thus increasing its effectivness in first aid as most MI's occur in the comunity. I agree that most of my Pharomogology exams and revision were carried out either hungover or VERY tired as a result of 24/7 revision, BUT i did remember some of it. (and its also in the "Pharmocology Bible") Regards, Bethan Regards, Bethan
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WelshMedic wrote:Asprin thins the blood. You are having a larf now. Aspirin is NOT a blood thinner, nor a throbolytic. It is an NSAID that also has antiplatelet properties. In ACS / MI it works as a platelet aggregation, or COX-1 inhibitor, which means it will act to curtail any further accumulation of platelets in the vessel (in dumb down speak, it makes the platelets ‘slippery” so they can no longer adhere to the surface of the vessel, or partially-formed thrombus which will cause it to increase in size, causing further ischemia or infarct). When people on daily ASA cut themselves shaving, it only takes longer to clot because the effect on platelet aggregation is delayed. Nothing to do with being a blood thinner. Those HCP’s amongst us can quite readily give ASA if the patient is already on Coumadin, or other Vitamin-K antagonists, as we know it affects a different part of the clotting cascade. Of course, you already knew that didn’t you “Doc”?
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Actualy, the fact that platlets become "Slipery" results in the consistency of the blood being alot thinner! (therfore it does thin the blood). Also as the platlets are "Slipery", the platlets causing the clot also become fragmented and start to soften. As i said, it is not as good as a throbolytic drug but is still effective in the breakdown of a CA clot. Regards, Bethan
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Ohhh of course. So what would you say the normal theraputic PT-PTT range would be with ASA (as applies to all other blood thinners)?
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Prothrombin and partial thromboplastin time have nothing at all to do with asprin! Regards, Bethan (anyhow im not going to go any further on this topic as I feel its going to lead in arguments)
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Anyone could have googled what the letters stood for. I think you have been sussed. Good effort though  until you tried to get technical 
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If you are a registrar making statements such as this, it is important you continue, unless you are not sure of what you are actually saying!
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I certainly hope that Welsh Medic is genuine, because with my limited medical knowledge a lot of things he or she has said on this forum have been quite interesting. It does make you realise that with all the expertise available on this site, if you're not genuine, or try to bluff your way through a topic then you'll get caught out eventually, by someone who DOES KNOW WHAT THEY'RE TALKING ABOUT. As I always say "You never know who you are actually talking to" Thanks Derek MBE, Bsc, Doctor of Brain Disorders, Sheep Shagging Technician, Haggis Chaser. And many more from eBay........ derek2007-04-08 14:01:10
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I do believe that WelshMedic has some healthcare experience & knowledge, and is undoubtedly adding some important contributions, but I'm highly dubious as to whether she is an A&E registrar: there have been a few other slips besides this one which have made me wonder!
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Slips? Such as? And yes i AM actually a registrar in accident and Emergency Locuming between Several major a+e departments and sever Local Accident Centers. You can always email me your cenerns and i would be happy to supply my GMC ref. number 
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Actualy i will not be a supplying GMC ref. Number (can cause too many problems) And i dont need to prove myself on a forum either! Regards, Bethan (plus it would be a bit sad pretending to be over qualified - one of my pet hates - first aiders who try to be "Medics")
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Very professional of you "Doc" Anyone who claims that aspirin is a blood thinner and, or a clot buster is NOT a Doctor. Anyone who would advocate leaving an angulated deformity (Fx femur) in situ without assessing distal circulation is NOT a Doctor. Anyone who states that 6 litres of saliva are needed to transmit an infection from host to host is NOT a Doctor. Ever heard of glandular fever “Doc” AKA mononucleosis, AKA the “kissers disease”? I have my doubts as to whether you are even Welsh. As a final remark, putting your heroic self in the picture on 7/7 is in the worst possible taste. Perhaps you can provide a link to that conference you were at on that day.grant12007-04-08 15:32:27
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1 - Even if Circulation was not present, Most first aiders are not trained in tracton so there is nothing thet can do.
2 - Its a common fact that asprin "Thins the blood" - not a thrombolytic process but mechanical process on platlets.
3 - In the post about CPR we were talking about HIV, Hep. B etc. and these can not be passen on oraly!!! unless excessive amounts of Saliva are "Consumed"(OBI's)
4 - The confrence that took place was a meeting of registrars, SHO's and GP's working in Local Accident Centes from Wales, Scotland and England meeting to discuss the benefits and disadvantages of more Local Accident Centers opening around the county which as a result takes the strain from major a+e departments.
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I am not having a go.....far from it. I ask to you continue with your discussion, don`t treat us as if we are stupid, this may say first aid cafe, though there are SRParas, and very experienced people here, I hark back to patronising remarks about HCA`s.....most HCA`s are more valuable than nurses in nursing homes......point of fact! If you have a point further discuss,don`t throw the dummy out the pram! It really does nothing for credibility here. I have mentioned this before.....please don`t give me the one.......I`ll make posts, when further questioned back off......debate helps us learn......maybe you can learn some more too.......we all can, thats why we are here!
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I agree scotty - we are always learning. But when people start making snide comments and questioning over 15 years of medical school and medical training then what is the point of discussion as it gets no further due than arguments!
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WelshMedic wrote:2 - Its a common fact that asprin "Thins the blood" - not a thrombolytic process but mechanical process on platlets. Wrong, for someone who claims to have spent all those years at medical school, you really have a problem with pharmacokinetics don't you? Hungover during all those boring lectures too? Quote:In the post about CPR we were talking about HIV, Hep. B etc. and these can not be passen on oraly!!! unless excessive amounts of Saliva are "Consumed"(OBI's) Quote: The confrence that took place was a meeting of registrars, SHO's and GP's working in Local Accident Centes from Wales, Scotland and England meeting to discuss the benefits and disadvantages of more Local Accident Centers opening around the county which as a result takes the strain from major a+e departments. Of course, no external link. So we only have your word, which at the moment isn't worth much. Taking the micky is one thing, but you are making a mockery of the genuine posters who want to learn, by giving them ill-advised and completely untrue advice. Think you should fess up, or you are going to have to do a lot of research for your future posts if you want to keep up the act.
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I'm not even going to stress myself out arguing with you Grant! I dont need to prove myself in a forum! regards, Bethan
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grant, let's take it easy shall we? I don't think it's unreasonable, for example, for a reader to presume that HIV was the infection under discussion. Everyone is prone to the odd error from time to time as well, for example I'm pretty sure you mean pharmacodynamics rather than pharmacokinetics. Whilst I think there is some question over welshmedic's qualifications, she nevertheless is providing useful input, and there is no need to pick apart every minor mistake or omission she may have made - let's stick to rational debate shall we? By all means point out glaring errors such as this one, but there's no need to nitpick.
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Bethan, word of advice....... I`m just a torn faced git, take no note of me.... If you are right, then display your knowledge! showing others you are not a shyster is always good. Don`t give up without showing you are the person you say you are.....it detracts all the abuse then to others. I like showing others exactly how good I am, why don`t you?  personally I dislike muppets......we have enough of those here, don`t be bullied into not posting! scottydog2007-04-08 17:21:24
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